project |
|
---|---|
Name/scientific name |
THIOGUANINE
|
Self-financed or subsidized by the Hospital Authority |
Hospital Authority Drug Formulary
|
Indications |
acute lymphoblastic leukemia, chronic myelogenous leukemia, acute myelogenous leukemia
|
body system |
Cancer and immune system
|
type |
Cytotoxic drugs
|
Thioguanine is a drug used to treat certain types of leukemia. It belongs to a class of drugs called antimetabolites, which work by interfering with the growth of white blood cells. This drug is commonly used to treat acute lymphoblastic leukemia and other blood-related diseases.
While taking thioguanine, patients will need regular blood tests to monitor the drug's effects on white blood cells and other blood components. Additionally, patients should avoid receiving live vaccines while taking thioguanine as this may lead to infection.
While taking thioguanine, patients may experience some side effects, including nausea, vomiting, diarrhea, and mouth sores. If serious side effects or discomfort occur, seek medical attention immediately.
Be sure to use thioguanine correctly and as directed by your doctor, and pay close attention to any unusual symptoms while using it.
Instructions for use: Take THIOGUANINE orally daily. It is recommended to take it after meals to reduce gastric discomfort. Avoid eating it with sulfur-containing foods such as onions and garlic to avoid affecting the efficacy of the medicine. While taking it, you should avoid engaging in activities that require high alertness, such as driving a motorcycle or operating machinery.
Dosage Guidelines: The starting dose for adults is 2 to 3 mg/kg daily, taken in 2 to 3 divided doses. Physicians may adjust dosage based on patient response and tolerability. The dosage for children is based on weight and age. The usual starting dose is 1 to 2 mg/kg daily, taken in 2 to 3 divided doses. During the use of THIOGUANINE, doctors should regularly monitor and adjust the dosage to ensure efficacy and safety.
THIOGUANINE is a drug used to treat certain blood cancers and inflammatory bowel disease, but it also has some side effects. Common ones include digestive problems such as vomiting, diarrhea and mouth ulcers; making people feel tired or dizzy; possibly affecting liver function; and increasing the risk of infection. When using THIOGUANINE, pay attention to your body's reaction and follow your doctor's advice. If severe discomfort occurs, you should stop using the drug immediately and seek medical treatment.
Drug name: THIOGUANINE
Taboo:
1. It is contraindicated for those who are allergic to THIOGUANINE. It may cause severe allergic reactions, including skin redness and swelling, difficulty breathing, etc.
2. Pregnant women should avoid using THIOGUANINE as it may cause damage to the fetus and should be used with caution under the guidance of a physician.
3. Breastfeeding women should not use THIOGUANINE as it may have adverse effects on the baby. Please consult a physician before considering use.
4. Patients with severe liver disease should avoid using THIOGUANINE as it may lead to worsening of liver function. They need to consult a physician to choose a suitable alternative drug.
5. Patients with severe myelosuppression should not take THIOGUANINE, as it may aggravate the condition, and the treatment plan needs to be adjusted according to the physician's recommendations.
The above are the contraindications of THIOGUANINE. You should read the drug instructions carefully or consult a doctor before use to ensure safe and effective use of the drug.
Precautions for use: Follow your doctor's prescription instructions when using this medication. During use, blood tests should be performed regularly to monitor the effects of the drug on the body. Avoid concurrent use with drugs containing sulfonamides. If serious side effects occur, such as severe skin reactions or severe digestive tract problems, seek medical attention immediately.
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Pregnant women should avoid using thioguanine. Thiopurines may have serious effects on the fetus during pregnancy, including congenital heart abnormalities, liver damage, and bone development problems. If you are receiving thiopurine therapy and plan to become pregnant, tell your doctor right away. Your doctor may recommend that you stop using the medication or switch to another safer treatment.
If you find that you have used thiopurines during pregnancy, consult your doctor immediately. A doctor will assess the potential risks and give appropriate advice. Please do not stop taking thiopurine or make any voluntary changes to your treatment plan without the guidance of a professional doctor.
All in all, if you take thiopurines during pregnancy, you must inform your doctor immediately and handle it according to the doctor's recommendations to protect the health of you and your fetus.
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