project |
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Name/scientific name |
PROTAMINE SULPHATE
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Self-financed or subsidized by the Hospital Authority |
Hospital Authority Drug Formulary
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Indications |
Heparin overdose, surgical bleeding, thromboembolism, cardiac surgery
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body system |
cardiology
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type |
Anticoagulants and protamine
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Protamine sulphate is a drug used to treat bleeding caused by heparin overdose. It reduces the risk of bleeding by neutralizing the anticoagulant effect of heparin. Protamine sulfate is commonly used during surgery or other situations where rapid reversal of the effects of heparin is required. In Hong Kong, doctors may use protamine sulfate when heparin overdose causes bleeding. Patients should have their blood pressure and coagulation function closely monitored while receiving this medication to ensure effectiveness and safety. Protamine sulfate may cause allergic reactions, so patients should inform their doctor of any history of allergies. When using protamine sulfate, strictly follow your doctor's recommendations and dosage, and avoid adjusting the dosage or frequency on your own.
HOW TO USE: Protamine Sulphate is usually given as an injection and must be administered by a healthcare professional in a medical facility. The drug can be given by intravenous injection or subcutaneous injection. When using it, you should follow your doctor's instructions and do not adjust the dosage or usage by yourself. Before injection, it should be confirmed that there are no suspended solids or abnormal changes in the drug.
Dosage Guidelines: The usual dose of protease sulfate for adults is 25 to 50 mg each time, depending on the severity of the patient's condition, and may be repeated every 4 to 6 hours. For children, dosage is based on age and weight, usually 1 to 2 mg per dose. For special groups, such as the elderly or those with liver and kidney dysfunction, the dose should be adjusted according to individual conditions.
When using protease sulfate, you should pay attention to possible allergic reactions. If allergic symptoms occur, you should stop using it and seek medical advice immediately. At the same time, patients should avoid eating high-fat foods during use to ensure effective absorption of the drug. If you have any questions or adverse reactions, you should consult your physician immediately.
Protamine sulphate is a drug used to reverse heparin overdose. This drug has some side effects that may cause allergic reactions, such as skin itching, redness, swelling and rash. In rare cases, severe allergic reactions may occur, including difficulty breathing, chest pain, and coma. In addition, the use of Protamine sulphate may also cause common side effects such as hypotension, palpitations, and headaches. If any unusual reactions occur, stop using the medication immediately and seek medical advice.
Drug contraindications mean that patients should not use a certain drug under certain circumstances to avoid causing serious adverse reactions or harming health. The following are contraindications for PROTAMINE SULPHATE:
1. Patients who are allergic to protamine or other similar drugs should not use protamine sulfate because it may cause severe allergic reactions, including skin redness and swelling, difficulty breathing, and even shock.
2. Patients with pulmonary hypertension should avoid using protamine sulfate because it may increase blood pressure and aggravate the condition.
3. Patients with heart disease should consult a doctor before using protamine sulfate, because this drug may have an impact on cardiac function, especially in patients with adverse effects on the cardiac conduction system.
In short, before using protamine sulfate, you should understand your health condition in detail and use it under the guidance of a doctor to avoid the occurrence of adverse reactions. If the patient has one of the above contraindications, he should inform the medical staff immediately to avoid health risks.
Protamine sulfate is a medication used to reverse the effects of heparin, an anticoagulant medication. It should be used cautiously in patients with a history of hypersensitivity reactions to fish or fish products, as protamine sulfate is derived from fish sperm. Close monitoring is recommended to prevent allergic reactions. Consult a healthcare professional before use.
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Use of Protamine Sulphate during pregnancy may cause harm to the fetus and should be avoided. Protamine Sulphate is mainly used to treat bleeding caused by anticoagulant overdose, and its safety for pregnant women and fetuses is unknown. If you are pregnant or planning to become pregnant, you should seek advice from your doctor before using this medication. If you become pregnant while taking Protamine Sulphate, you should tell your doctor immediately. Your doctor will evaluate the balance between pregnancy and drug risks and recommend the most appropriate treatment option for you.
Please note that effective contraception should be used while using Protamine Sulphate to avoid pregnancy. If pregnancy occurs, your doctor should be told immediately so that they can provide appropriate advice and guidance. In conclusion, you should avoid using Protamine Sulphate during pregnancy and seek medical advice before using any medication.
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