project |
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Name/scientific name |
MELPHALAN
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Self-financed or subsidized by the Hospital Authority |
Hospital Authority Drug Formulary
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Indications |
Multiple myeloma, ovarian cancer, breast cancer, pediatric neuroblastoma
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body system |
Cancer and immune system
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type |
Cytotoxic drugs
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Melphalan is a chemotherapy drug used primarily to treat cancers such as multiple myeloma and ovarian cancer. It belongs to a class of drugs called alkalizers, which prevent the growth of cancer cells by interfering with their DNA replication. In Hong Kong, doctors may choose to use Melphalan as part of a cancer treatment regimen. This medication is usually given by intravenous injection, and the doctor will determine the dosage and frequency based on the patient's specific condition. The use of Melphalan may cause some side effects, including leukopenia, nausea, vomiting, and gastrointestinal discomfort. Patients should monitor closely and follow their doctor's instructions while receiving this medication. If you have any concerns or questions, please consult your doctor immediately.
Instructions for use: MELPHALAN is an oral medication and should be used under the guidance of a physician. It is usually recommended to take it on an empty stomach, i.e. 1 hour before or 2 hours after a meal. Please follow your doctor's advice and do not adjust the medication time at will. Foods containing grapefruit should be avoided during use as they may affect the effectiveness of the medicine. At the same time, patients should avoid participating in activities that require high alertness, such as driving or operating machinery, during use.
Dosage Guidelines: The dosage of MELPHALAN will be based on the patient's specific condition, including age, weight, and disease severity. Generally speaking, the starting dose for adults is 0.15-0.2 mg/kg body weight per day, divided into 2-4 doses. For children, the dosage needs to be adjusted based on their weight and physical condition, and a pediatrician should be consulted. During treatment, the dose may be adjusted based on the patient's response and blood test results. Please do not increase or decrease the dose on your own. If you have any questions or discomfort, you should consult your doctor immediately.
MELPHALAN is a chemotherapy drug used to treat a variety of cancers, including myeloma and lymphoma. Its side effects include vomiting, diarrhea, dizziness, fatigue and bone marrow necrosis. Some patients may experience more serious side effects, such as an increased risk of infection, anemia, bleeding problems and long-term effects on fertility. If you notice any unusual reactions, you should consult your doctor immediately. Before seeing a doctor, you should keep a record of your symptoms and body reactions to help the doctor evaluate the situation and adjust treatment plans.
MELPHALAN is a chemotherapy drug used to treat many types of cancer, but it is contraindicated in some cases. The following situations should be avoided when using MELPHALAN:
1. Hypersensitivity reactions: Patients who are allergic to MELPHALAN or any of its ingredients should not use this drug. Allergic reactions may include symptoms such as red and swollen skin, difficulty breathing, and swelling of the throat. In severe cases, it may lead to shock.
2. Contraindications for pregnant women: Pregnant women should avoid using MELPHALAN as the drug may cause serious effects on the fetus, including malformations and developmental problems.
3. Severe myelosuppression: Patients with severe myelosuppression should not use MELPHALAN because the drug may further reduce the number of red blood cells, white blood cells and platelets in the blood and increase the risk of infection and bleeding.
4. Hepatic insufficiency: Patients with severe hepatic insufficiency should avoid using MELPHALAN because the liver cannot effectively metabolize the drug, which may cause the drug to accumulate in the body and cause toxic reactions.
Before using MELPHALAN, patients should inform their doctor about their allergy history, pregnancy status, bone marrow function, and liver function to ensure the safe use of this drug. If you have any adverse reactions or questions, seek help from your doctor immediately.
MELPHALAN
Precautions for use: Please follow your doctor's instructions and do not adjust the dosage yourself. During use, you should try to avoid contact with other people's body fluids and maintain good personal hygiene habits. If you experience any discomfort or side effects, you should seek medical advice immediately.
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Pregnant women should avoid using MELPHALAN as it may cause serious effects on the fetus. Using MELPHALAN during pregnancy may cause fetal malformations or other health problems. If you are planning to become pregnant or are pregnant, you should tell your doctor immediately and discuss appropriate alternative treatments.
During treatment with MELPHALAN, patients should strictly follow their doctor's recommendations and monitoring. Female patients should use effective contraception to avoid pregnancy and exposure of the drug to the fetus.
If you suspect you may be pregnant or plan to become pregnant, tell your doctor immediately. Your doctor can evaluate your situation and provide appropriate advice and guidance. Remember, proper preparation and careful handling are important parts of ensuring the health of you and your baby.
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