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project

Name/scientific name

HYDROXYUREA

Self-financed or subsidized by the Hospital Authority

Hospital Authority Drug Formulary

Indications

Chronic myeloid leukemia, multiple myeloma, myelofibrosis, myeloproliferative disorders, sickle cell anemia

body system

Cancer and immune system

type 

Cytotoxic drugs

Drug introduction

Hydroxyurea is a drug used to treat leukemia and iron transporter disorders. It reduces the growth and proliferation of abnormal cells by inhibiting DNA synthesis. This medicine may also be used to treat certain types of myelodysplastic disease. In Hong Kong, hydroxyurea is commonly used to treat chronic myelogenous leukemia, sideroportin disorders, and specific sideroportin disorders.

When using hydroxyurea, patients should use the drug strictly according to the doctor's instructions and do not adjust the dosage or stop using it on their own. During use, blood tests should be performed regularly to monitor treatment effects and possible side effects. Common side effects include anemia, nausea, vomiting, and mouth sores. If serious side effects occur, seek medical attention immediately.

Do not use hydroxyurea with other medicines unless approved by your doctor. During use, avoid contact with pregnant women or women planning to become pregnant. If you have any questions or discomfort, you should consult your doctor immediately.

Dosage

Instructions for use: Please take this drug according to your physician's instructions. It is usually taken at a fixed time each day, on an empty stomach or with food. Do not adjust the dosage or stop using it on your own to avoid affecting the therapeutic effect. While taking it, avoid drinking alcoholic beverages and stay well hydrated.

Dosage Guidelines: The usual starting dose for adults is 15 mg/kg body weight per day, taken in divided doses. Physicians may adjust the dose according to individual circumstances, and the maximum dose does not exceed 35 mg/kg body weight per day. The dosage for children needs to be adjusted according to age and weight. The starting dosage is generally lower, and the doctor will make adjustments based on the condition and response. Please follow your physician's advice closely and perform regular medication monitoring to ensure safe and effective use.

side effect

HYDROXYUREA is a drug used to treat leukemia and other blood disorders, but it has some common side effects, including dizziness, nausea, vomiting and diarrhea. Some patients may also experience dry skin, thinning or discoloration of hair. People using this medication may feel tired and develop mouth sores. In addition, HYDROXYUREA may also affect platelet production and increase the risk of bleeding. If serious side effects occur, consult your doctor immediately.

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Taboo

HYDROXYUREA is a drug used to treat certain types of leukemia, iron infusion-dependent anemia and certain types of myelodysplastic disorders. However, the following contraindications should be noted when using HYDROXYUREA:

1. Contraindications for pregnant women: HYDROXYUREA may cause harm to the fetus and should be avoided during pregnancy and pregnancy planning.

2. Contraindications for lactating women: HYDROXYUREA may be passed to the baby through breast milk, so lactating women should not use it.

3. Contraindications for patients with a history of severe myelosuppression: HYDROXYUREA may cause damage to bone marrow function, so patients with a history of severe myelosuppression should not use it.

4. Contraindications in patients with hepatic insufficiency: The metabolism of HYDROXYUREA mainly occurs in the liver. If the patient has hepatic insufficiency, it may affect drug metabolism and should be avoided.

5. Contraindications in patients with renal insufficiency: HYDROXYUREA is mainly excreted through the kidneys. If the patient has renal insufficiency, it may increase the concentration of the drug in the body and should be avoided.

Before using HYDROXYUREA, patients should inform their doctor of all medical history and existing health conditions to ensure safe and effective use of the drug. If you have any discomfort or concerns, you should consult your doctor immediately.

Precautions

Hydroxyurea is a drug used to treat certain types of leukemia and other blood disorders. When using it, you should strictly follow the dosage recommended by your doctor and do not adjust the dosage on your own. Blood parameters should be monitored during use and medical examinations should be performed regularly to ensure efficacy and safety. If you have any discomfort or questions, you should consult your doctor immediately.

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  • Medication grading for pregnant women

    Pregnant women should use hydroxyurea with caution. This drug may cause harm to the fetus. You should tell your doctor if you are pregnant or planning to become pregnant. During use of hydroxyurea, female patients should actively avoid pregnancy and use reliable contraceptive measures. If you find out you are pregnant, you should notify your doctor immediately. Your doctor may need to monitor your pregnancy and fetal development while you are receiving treatment.

    Additionally, breastfeeding women should not use hydroxyurea because this drug may pass into breast milk and cause damage to the baby. If you are breastfeeding and need to use hydroxyurea, you should consult your doctor and stop breastfeeding while you are using it.

    Remember, hydroxyurea should be used as recommended by your doctor and follow all medical instructions. If you have any questions or concerns, please consult your doctor immediately. This helps ensure the health of you and your baby.

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