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drug database

project

Name/scientific name

GLYCERYL TRINITRATE

Self-financed or subsidized by the Hospital Authority

Hospital Authority Drug Formulary

Indications

Angina pectoris, chronic heart failure, hypertensive crisis

body system

cardiology

type 

Nitrates, calcium channel blockers, and other antianginal drugs

category

Pagination

Drug introduction

Nitroglycerin is a drug that dilates blood vessels and reduces the workload on the heart and is often used to treat angina pectoris. It relieves symptoms of cardiac ischemia by relaxing vascular smooth muscle, increasing the diameter of the vascular lumen, and reducing blood pressure and cardiac workload. Nitroglycerin is mainly used to relieve acute angina attacks and can also be used for preventive treatment. Patients usually place a nitroglycerin lozenge under the tongue or in the mouth and wait for the tablet to dissolve completely before swallowing it. When using nitroglycerin, you should follow your doctor's advice and not change the dose or frequency at will. Possible side effects include headache, low blood pressure, and dizziness. If serious adverse reactions occur, such as persistent headache or fainting, seek medical attention immediately. Talk with your doctor for more information about nitroglycerin.

Dosage

Directions for use: Place the glyceryl trinitrate drug under the tongue and allow it to be quickly absorbed in the mouth. Generally, it is not necessary to take it with meals, but it should be avoided with alcoholic beverages. Avoid heavy activities or operating machinery while using the drug.

Dosage Guidelines: For adults, the starting dose is 0.4 mg to 0.8 mg, which may be repeated every 5 minutes for up to 3 times. Dose adjustments should be made based on patient response, but the total dose should not exceed 3 mg. For children, lower doses are recommended and should be determined by a physician on a case-by-case basis. Always follow your doctor's instructions for using the medication and seek medical attention if necessary.

side effect

GLYCERYL TRINITRATE is a drug commonly used to treat heart disease, but it has some side effects that need attention. Some patients may experience dizziness, headache, nausea and low blood pressure after taking it. Some people may experience dry mouth, facial flushing, or heart palpitations. Long-term use may lead to drug resistance, requiring dosage adjustment. If you experience serious side effects such as difficulty breathing, chest pain, or abnormal heartbeat, seek medical attention immediately. When using GLYCERYL TRINITRATE, remember to take it according to your doctor's advice and avoid increasing or decreasing the dose on your own.

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Taboo

Drug Name: Glyceryl Trinitrate

Taboo groups:
1. It is contraindicated for those who are allergic to nitroglycerin or other nitrates as it may cause severe allergic reactions.
2. It is not suitable for patients who are taking phosphodiesterase-5 inhibitors (such as ivabradine), as simultaneous use may cause severe hypotension.
3. Patients after myocardial infarction, especially those with right ventricular myocardial infarction, should avoid using nitroglycerin.
4. Patients with a history of severe hypotension, shock, head trauma, intracerebral hemorrhage, glaucoma, hyperthyroidism, acute pericarditis, cardiac tamponade, etc. are prohibited from using nitroglycerin.
5. Patients who are concurrently taking phosphodiesterase-5 inhibitors (such as sildenafil) should avoid the use of nitroglycerin, which may cause severe hypotension.
6. Pregnant women should avoid using nitroglycerin, especially those in the third trimester of pregnancy, as it may cause harm to the fetus.

The above are people who are contraindicated for using nitroglycerin. Please consult a doctor or pharmacist for advice before use to ensure safe use of the medication.

Precautions

Glyceryl trinitrate is a drug used to relieve the symptoms of angina. When using it, be careful to avoid using it with alcohol to avoid increasing the risk of hypotension. During use, you should follow the doctor's advice and avoid stopping use suddenly to avoid rebound phenomenon. If you have any discomfort or questions, please consult your doctor immediately.

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