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project

Name/scientific name

GLYCERYL TRINITRATE

Self-financed or subsidized by the Hospital Authority

Hospital Authority Drug Formulary

Indications

Angina pectoris, chronic heart failure, hypertensive crisis

body system

cardiology

type 

Nitrates, calcium channel blockers, and other antianginal drugs

Drug introduction

Nitroglycerin is a drug that dilates blood vessels and reduces the load on the heart. It is often used to treat angina. It reduces the symptoms of cardiac ischemia by relaxing vascular smooth muscle, increasing the diameter of the vascular lumen, reducing blood pressure and cardiac load. Nitroglycerin is mainly used for the relief of acute angina pectoris attacks and can also be used for preventive treatment. Patients usually need to place nitroglycerin lozenges under their tongue or in their mouth and wait for the tablet to completely dissolve before swallowing. When using nitroglycerin, follow your doctor's advice and do not change the dosage or frequency. Possible side effects include headache, low blood pressure, and dizziness. If serious adverse reactions occur, such as persistent headache or fainting, seek medical attention immediately. Ask your doctor for more information about nitroglycerin.

Dosage

How to use: Place glyceryl trinitrate medication under the tongue and allow it to be quickly absorbed in the mouth. Typically, it is not necessary to take it with food, but use with alcoholic beverages should be avoided. You should avoid heavy activities or operating machinery while using the drug.

Dosing Guidelines: For adults, a starting dose of 0.4 mg to 0.8 mg may be repeated every 5 minutes up to 3 times. Dose adjustments should be made based on patient response, but the total dose should not exceed 3 mg. For children, lower doses are recommended and should be determined by a physician on a case-by-case basis. Be sure to follow your doctor's instructions when using your medications and seek medical attention if necessary.

side effect

GLYCERYL TRINITRATE is a drug commonly used to treat heart disease, but it has some side effects to be aware of. Some patients may experience dizziness, headache, nausea and hypotension after taking it. Some people may experience dry mouth, facial flushing, or heart palpitations. Long-term use may lead to drug resistance, requiring dose adjustment. If you experience serious side effects such as difficulty breathing, chest pain, or abnormal heartbeat, seek medical attention immediately. When using GLYCERYL TRINITRATE, remember to take it according to your doctor's recommendations and avoid increasing or decreasing the dosage on your own.

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Taboo

Drug name: Glyceryl Trinitrate

Taboo groups:
1. It is forbidden for those who are allergic to nitroglycerin or other nitrates, as it may cause severe allergic reactions.
2. Not suitable for patients who are taking phosphodiesterase-5 inhibitors (such as ivabradine). Simultaneous use may cause severe hypotension.
3. Patients after myocardial infarction, especially those with right ventricular myocardial infarction, should avoid using nitroglycerin.
4. Nitroglycerin is contraindicated in patients with a history of severe hypotension, shock, head trauma, intracerebral hemorrhage, glaucoma, hyperthyroidism, acute pericarditis, cardiac tamponade, etc.
5. Patients who are also taking phosphodiesterase-5 inhibitors (such as sildenafil) should avoid using nitroglycerin, which may cause severe hypotension.
6. Pregnant women should avoid using nitroglycerin, especially women in the third trimester of pregnancy, as it may cause harm to the fetus.

The above are contraindications for nitroglycerin. Please consult your doctor or pharmacist before use to ensure safe use.

Precautions

Glyceryl trinitrate is a drug used to relieve the symptoms of angina. When using it, care should be taken to avoid using it at the same time with alcohol to avoid increasing the risk of hypotension. During use, you should follow your doctor's advice and avoid sudden cessation of use to avoid rebound. If you have any discomfort or questions, you should seek medical advice immediately.

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