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Name/scientific name

BUROSUMAB

Self-financed or subsidized by the Hospital Authority

Hospital Authority Drug Formulary

Indications

X-linked hypophosphatemic rickets, hypophosphatemic rickets

body system

type 

Drug introduction

Burosumab is a drug used to treat adults and children with X-linked protein deficiency (XLH). XLH is a rare genetic disorder that prevents the body from properly absorbing phosphorus, affecting bone development and health.

Brosama acts on phosphate metabolism in the body, helping to increase the phosphorus content in bones and improve the risk of osteoporosis and fractures. Use of this medication requires a physician's prescription and injections as directed.

Side effects such as headache, abdominal pain, and fatigue may occur while using brosama. There may be discomfort at the injection site after the injection. If serious side effects or allergic reactions occur, seek medical attention immediately.

While using brosumab, patients should receive regular medical monitoring to ensure efficacy and safety. Please follow your physician's advice and instructions and return for regular check-ups.

Dosage

How to use: Inject once a week. The drug is injected subcutaneously by a medical professional. It is recommended that the injection be given at the same time on the same day. It does not need to be taken with food, but it can be injected before or after a meal. Injection sites should be rotated to avoid damage to subcutaneous tissue. Before injecting, make sure the medicine is free of foreign matter or discoloration.

Dosage Guidelines: Starting dose is 0.8 mg per kilogram per week, maximum not to exceed 150 mg per week. Dosage may be adjusted based on the patient's physiological condition and response to treatment. Dosing recommendations are similar for adults and children but are adjusted based on body weight. Please calculate the dose accurately according to the doctor's advice and do not adjust it yourself. If you have any questions, please consult a medical professional immediately.

side effect

BUROSUMAB is a drug used to treat osteomalacia and may cause some side effects. Common side effects include swelling, pain, or redness at the injection site, headache, feelings of fatigue, muscle pain, and joint pain. In rare cases, adverse reactions such as nausea, vomiting, diarrhea and rash may also occur. If you have serious side effects or discomfort while using BUROSUMAB, you should tell your doctor right away. Remember to use your medications as recommended by your doctor, and have regular checkups to monitor any potential side effects.

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Taboo

The drug BUROSUMAB is a drug used to treat bone diseases in adults and children, but there are contraindications to its use in certain cases. First, the use of this medication is contraindicated in persons with known sensitivity or allergy to BUROSUMAB or its ingredients. Secondly, BUROSUMAB should be avoided if the patient has conditions such as hypercalcemia or hyperthyroidism. In addition, pregnant and lactating women should use this drug with caution under the guidance of a doctor to avoid adverse effects on the fetus or baby. Finally, patients with severe renal impairment should avoid using BUROSUMAB as this may cause further health problems. Before using BUROSUMAB, patients should provide their doctor with detailed health status to ensure safe use of the drug, and receive regular examinations and monitoring as directed by their doctor. In summary, following your doctor's advice and instructions is key to ensuring safe and effective use of BUROSUMAB.

Precautions

BUROSUMAB

Precautions for use: This drug is only for patients with osteomalacia. It should be used according to the doctor's instructions and the dosage should not be adjusted by yourself. During use, you should be monitored by a doctor regularly, and if you experience any discomfort or side effects, you should inform your doctor immediately.

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  • Medication grading for pregnant women

    There are some important precautions to take when using burosumab when you are pregnant or planning to become pregnant.

    First, the use of burosumab should be avoided during pregnancy because of possible damage to the fetus. If you are taking this medication, you should tell your doctor immediately and discuss whether you need to stop using it or change your treatment regimen.

    Additionally, use of burosumab should be avoided with extreme caution during pregnancy as it may pose serious risks to the mother and fetus. You should maintain close contact with your doctor throughout your pregnancy to ensure your personal safety and health.

    In general, the use of burosumab should be avoided during pregnancy and your doctor's advice and instructions should be followed in all cases. If you have any questions or concerns, please consult your doctor immediately.

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