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project

Name/scientific name

ARGATROBAN

Self-financed or subsidized by the Hospital Authority

Hospital Authority Drug Formulary

Indications

Thrombotic thrombocytopenic purpura, acute coronary syndrome, deep vein thrombosis, pulmonary embolism

body system

cardiology

type 

Anticoagulants and protamine

Drug introduction

Argatroban is an anticoagulant drug commonly used to prevent or treat blood clot disorders such as deep vein thrombosis or pulmonary embolism. It prevents thrombosis by inhibiting thrombin activity. Argatroban is suitable for patients who are allergic to heparin or who are unable to use heparin. When using Argatroban, strictly follow your doctor's recommendations and the dosing instructions on the package insert. Possible side effects include bleeding, which requires close monitoring. Also, avoid interactions with other medications, especially those that affect blood clotting. While using Argatroban, check coagulation indicators regularly to ensure treatment effectiveness and reduce the risk of adverse reactions. If you have any adverse reactions or questions, seek help from your doctor immediately.

Dosage

How to use: Please use this medicine according to the instructions of your doctor or pharmacist. Usually the daily dose is divided into multiple doses, which are recommended to be taken at the same time point. Can be taken with or without food. During use, avoid eating too much foods containing vitamin K, such as spinach, cabbage, etc. At the same time, you need to avoid participating in high-risk activities, such as rock climbing.

Dosage Guidelines: The starting dose for adults is 2 mcg/kg/minute as an intravenous infusion, with duration based on the patient's condition, usually 3 to 7 days. Dosage may be adjusted based on the patient's coagulation parameters. For pediatric patients, the dose will be based on weight and condition, please ask your physician to determine the appropriate dose. Do not adjust the dosage or stop using this medicine on your own, as this may affect the therapeutic effect.

side effect

ARGATROBAN is an anticoagulant used to prevent and treat thrombosis. Common side effects include bleeding, bruising, headache, dizziness, gastrointestinal upset, and red skin. Serious side effects may include severe bleeding, allergic reactions, liver damage, etc. When using ARGATROBAN, you should pay close attention to abnormal symptoms, such as persistent bleeding, vomiting blood, melena, etc., and seek medical advice immediately. While using this medicine, you should avoid activities or situations that may cause bleeding, such as cuts and surgeries. If in any doubt, you should seek medical advice.

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Taboo

Drug name: Argatroban

Contraindications:
1. Those who are allergic to Argatroban or have severe allergic reactions.
2. Patients with active bleeding or high risk of bleeding.
3. Patients with severe liver impairment. Because Argatroban is mainly metabolized by the liver, impaired liver function may lead to drug accumulation.
4. Suffering from intracranial hemorrhage or other conditions that increase the risk of serious bleeding.
5. Patients with severe hypertension, as Argatroban may increase the risk of bleeding.
6. Pregnant or lactating women should use Argatroban under the guidance of a physician.

Before using Argatroban, patients should inform their physician about allergic reactions, bleeding conditions, liver function conditions, high blood pressure, and pregnancy or breastfeeding. If you have any of the above contraindication symptoms, you should stop using Argatroban immediately and seek medical assistance. If patients have any questions or are unsure whether Argatroban is suitable for use, they should seek the advice of a healthcare professional.

Precautions

ARGATROBAN

Precautions for use: This drug is an anticoagulant and can only be used with a physician's prescription. Please use it strictly according to the doctor's instructions and do not adjust the dosage by yourself. Coagulation function should be closely monitored during use. If unexplained bleeding or other adverse reactions occur, seek medical attention immediately.

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  • Medication grading for pregnant women

    Agatipolamide is an anticoagulant commonly used to prevent deep vein thrombosis. Pregnant women should avoid using agatepamide during pregnancy because this drug may cause adverse effects on the fetus.

    If you are planning to become pregnant or are already pregnant, tell your doctor right away. Your doctor will help you assess your risks and find the best treatment option for you. Do not stop using agatepamide without your doctor's advice as this may lead to the development of blood clots.

    During pregnancy, it is important to follow your doctor's recommendations. Make sure you stay in close contact with your doctor to stay informed of any possible risks or issues. If you have any questions or concerns, please feel free to talk to your doctor. Maintaining good health is the best way to keep you and your baby safe.

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