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project

Name/scientific name

ANTIRABIES IMMUNOGLOBULIN (HUMAN)

Self-financed or subsidized by the Hospital Authority

Hospital Authority Drug Formulary

Indications

Rabies

body system

Immunization preparations and vaccines

type 

Immunoglobulin

Drug introduction

Antirabies immune globulin (human) is a drug used to prevent rabies infection. It contains antibodies that help the body fight the rabies virus. Antirabies immune globulin is often given along with the rabies vaccine after a bite or scratch from a potentially rabid animal. Immunoglobulins work to provide immediate protection, while vaccines help the body build long-term immunity.

When using anti-rabies immune globulin, vaccination should be done as early as possible and in accordance with the doctor's recommendations. Adverse reactions such as local pain and swelling at the injection site may occur after the injection, but most people tolerate it well. If serious adverse reactions occur, seek medical attention immediately.

In Hong Kong, anti-rabies immune globulin is usually injected by a medical professional in a hospital or clinic. Please follow your doctor's advice and get vaccinated promptly to prevent rabies infection.

Dosage

How to use: Antirabies immune globulin (human source) is a drug used to prevent rabies infection. It is usually used after a bite or scratch from a dog, cat, or other animal that may carry the rabies virus. The medication needs to be injected around the injured area and into the wound by a medical professional. Provides immediate protection when used before or at the same time as rabies vaccination.

Dosage Guidelines: Dosage for adults and children is the same and is based on body weight. The starting dose is 20 IU/kg and the maximum dose is not to exceed 40 IU/kg. If the patient weighs more than 40 kg, the maximum dose is 800 IU. In cases of multiple injury sites or large wounds, dosage may need to be adjusted. In special cases, your doctor may adjust the dosage to ensure effectiveness. Avoid drinking alcohol during use and follow your doctor's recommendations for further vaccinations.

side effect

ANTIRABIES IMMUNOGLOBULIN (HUMAN) is a drug used to prevent rabies, but it may cause some side effects when used. Common side effects include pain, redness, swelling, and warmth at the injection site. A few patients may experience allergic reactions, such as skin redness and swelling, difficulty breathing or dizziness. In rare cases, severe allergic reactions may occur, including shortness of breath, increased heartbeat, and a drop in blood pressure. If any unusual symptoms occur, seek medical attention immediately. You should pay close attention to your reactions and follow your doctor's advice while using this medication.

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Taboo

Please note that the following are contraindications for anti-rabies immune globulin (human use):

1. Patients who are allergic to any component of anti-rabies immune globulin are prohibited from using this drug. If you have ever had an allergic reaction to an immunoglobulin product or other medicine, you should tell your doctor right away.

2. Pregnant women should use anti-rabies immune globulin with caution and please inform your doctor before use. Although there is currently insufficient evidence that this drug is harmful to the fetus, it should be used with caution during pregnancy.

3. Patients with autoimmune diseases should avoid the use of anti-rabies immune globulin as it may cause allergic reactions or aggravate existing diseases.

4. If you are receiving other immunomodulatory treatments, please inform your doctor before using anti-rabies immune globulin to avoid the occurrence of adverse reactions or interactions.

Remember, you should consult your doctor or pharmacist before using any medicine to make sure you understand contraindications and follow professional advice.

Precautions

Anti-rabies immunoglobulin (human): Please follow the doctor's instructions when using it and inject it into the injured area in time to prevent rabies infection. If you have any discomfort or allergic reaction, seek medical attention immediately.

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  • Medication grading for pregnant women

    Human immunoglobulin antirabies drugs should be used with caution during pregnancy. Patients who become pregnant during treatment or after vaccination should inform their doctor immediately. Your doctor will evaluate the risks and benefits and decide whether to continue using this medication. Patients should watch for any unusual symptoms during pregnancy, such as skin reactions or allergic reactions. At the same time, you should also be alert to whether the drug may cause potential risks to the fetus.

    If this medication must be used during pregnancy, your doctor will recommend following a specific dosage and frequency, as well as regular checkups to monitor the health of the patient and the fetus. Patients should avoid adjusting dosage or stopping medication on their own and should strictly follow their doctor's recommendations and instructions.

    In short, special attention needs to be paid to the use of human immunoglobulin anti-rabies drugs during pregnancy, and they must be used with caution under the guidance of a doctor to ensure the safety of the patient and fetus.

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