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Name/scientific name

ANTI-D IMMUNOGLOBULIN (HUMAN)

Self-financed or subsidized by the Hospital Authority

Hospital Authority Drug Formulary

Indications

Hemolytic disease of the newborn, Rh blood group incompatibility, autoimmune thrombocytopenia, Rh immunoprophylaxis during pregnancy, post-transfusion purpura

body system

Immunization preparations and vaccines

type 

Immunoglobulin

category

Pagination

Drug introduction

Anti-D immune globulin (human source) is a drug used to prevent maternal and fetal blood incompatibility caused by Rh blood group incompatibility. During pregnancy, if the mother is Rh positive and the fetus is Rh negative, the mother may produce antibodies that attack the fetus' red blood cells, causing anemia or even death of the baby. Anti-D immune globulin (human source) prevents the mother from forming these harmful antibodies, thereby protecting the fetus from damage. This medication is usually given late in pregnancy and may also be used during miscarriage, C-section, or other situations. In Hong Kong, doctors may recommend that pregnant women receive anti-D immunoglobulin injections to prevent problems caused by Rh blood group incompatibility. Use this medication according to your doctor's advice and instructions to ensure the health of mother and baby.

Dosage

Instructions:
- This medicine is usually injected into a muscle or vein by a health care provider.
- It is generally recommended to receive injections at medical institutions. Please do not inject yourself.
- Sometimes required during pregnancy, please follow your physician's instructions.

Dosage Guidelines:
- Adults: 200 mcg/kg body weight per injection is usually recommended.
- Children: Dosage should be determined based on body weight and physician recommendation, do not adjust by yourself.
-The starting dose should be determined by the physician and adjusted to the patient's specific condition.

Please note:
- Please inform your doctor if you have any allergies or other drug use before use.
- Concomitant use with certain medications or activities should be avoided, follow your physician's advice.
- If you have any discomfort or questions, please consult medical staff immediately.

side effect

ANTI-D IMMUNOGLOBULIN (HUMAN) is a drug used to prevent premature birth caused by Rh blood group incompatibility. Side effects of this drug include redness, swelling, pain, or warmth at the injection site. Sometimes there are also digestive system reactions such as headache, nausea, vomiting or diarrhea. Rarely, allergic reactions such as rash, difficulty breathing, or swelling of the throat may occur. If you experience serious side effects, such as shortness of breath or rapid heartbeat, seek medical advice immediately. It is recommended to consult a doctor before use to ensure safe and effective use of the medication.

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Taboo

ANTI-D IMMUNOGLOBULIN (HUMAN) is a drug used to prevent Rh-negative pregnant women from developing antibodies after exposure to Rh-positive blood. However, ANTI-D IMMUNOGLOBULIN (HUMAN) is not suitable for everyone and the following are some contraindications:

1. People who are allergic to or have a history of allergies to ANTI-D IMMUNOGLOBULIN (HUMAN) should not use this drug. Allergic reactions may include symptoms such as skin redness and swelling, difficulty breathing, dizziness, and in severe cases, shock symptoms.

2. People with immune system diseases or immune system dysfunction should use ANTI-D IMMUNOGLOBULIN (HUMAN) with caution as it may cause an excessive immune response.

3. Pregnant women in early pregnancy (before 20 weeks) or those with a history of miscarriage should use this drug with caution and under the guidance of a physician.

4. People with thrombocytopenia, coagulation abnormalities or other blood diseases should avoid using ANTI-D IMMUNOGLOBULIN (HUMAN) to avoid aggravating the condition.

Before using ANTI-D IMMUNOGLOBULIN (HUMAN), patients should inform their physician about their allergies, disease history, and other medications they are currently taking to ensure safe use. If you have any adverse reactions or questions, you should check with your doctor immediately.

Precautions

Precautions for use: This drug is usually used to prevent Rh immune conflict between Rh-negative pregnant women and Rh-positive fetuses. Before using this medication, you should talk to your doctor to make sure it is appropriate for your condition. Please use this drug strictly according to your doctor's recommendations and avoid adjusting the dosage or usage on your own. If any adverse reactions occur, seek medical advice immediately.

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  • Medication grading for pregnant women

    If you need to use anti-D immunoglobulin (human) during pregnancy, you should pay attention to the following:

    1. Anti-D immunoglobulin (human) is safe to use during pregnancy as it is prescribed by a doctor.

    2. If you need to use anti-D immune globulin (human) during pregnancy, please inform your doctor of your pregnancy.

    3. If you have any allergic reactions or adverse reactions, please inform your doctor immediately.

    4. When performing treatment, be sure to follow your doctor's advice and instructions and do not change the dosage or stop use on your own.

    5. If you have any questions or concerns, please feel free to communicate with your doctor.

    In conclusion, it is safe to use anti-D immune globulin (human) during pregnancy, but make sure you are always in close contact with your doctor to ensure the health of you and your baby.

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