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project

Name/scientific name

AGALSIDASE BETA

Self-financed or subsidized by the Hospital Authority

Hospital Authority Drug Formulary

Indications

Fabry disease

body system

type 

category

Pagination

Drug introduction

Agalsidase beta is a drug used to treat Fabry disease. Fabry disease is a rare genetic disorder that primarily affects the kidneys, heart, and nervous system. Agalsidase beta is an enzyme preparation that can supplement the α-galactosidase deficiency in patients with Fabry disease. This helps reduce abnormal accumulation of glycolipids in the body, thereby improving symptoms and preventing organ damage. Treatment is usually given intravenously, and the frequency and dosage are based on the patient's specific condition. Some common side effects may occur while using Agalsidase beta, including injection site reactions, headache, fatigue, etc. Patients should receive regular medical monitoring while using the drug to ensure efficacy and safety. If you have any discomfort or questions, you should consult your doctor immediately.

Dosage

Instructions:
AGALSIDASE BETA is an injection that should be administered by professional medical staff in medical institutions. Injections are usually given once a week and can be in the buttocks, thigh, or upper arm. Patients should follow their physician's instructions and should not adjust the dosage or discontinue use on their own.

Dosage Guidelines:
- Adult dosage: Starting dose is 1 mg/kg body weight per week, maximum not to exceed 3 mg/kg body weight. Physicians may adjust dosage based on patient response and severity of condition.
- Pediatric dosage: The starting dose is usually 1 mg/kg body weight per week, and the physician will adjust it based on the child's age and weight. When used by children, the dosage should be adjusted strictly in accordance with the physician's recommendations.

While using AGALSIDASE BETA, patients should avoid participating in overly strenuous exercise or activities to avoid affecting the efficacy of the drug. Make sure the injection site is clean before injecting and follow the advice of your medical team. If you have any discomfort or questions, you should consult a physician immediately.

side effect

AGALSIDASE BETA is a drug used to treat Fabry disease. Some patients may experience side effects after use, including headache, muscle pain, fatigue, fever, skin redness and swelling, nausea, diarrhea, etc. Some patients may also experience allergic reactions, such as itchy skin, difficulty breathing, and throat swelling. If serious side effects occur, consult your doctor immediately. When using AGALSIDASE BETA, you should pay close attention to your physical condition and communicate with your doctor to avoid unnecessary risks.

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Taboo

AGALSIDASE BETA is a medicine used to treat Fabry disease. Before using AGALSIDASE BETA, patients need to be aware of some contraindications. First, AGALSIDASE BETA should not be used by patients who are allergic to this drug. If the patient is allergic to any ingredient in this medicine, he should stop using it immediately and consult his doctor. Secondly, women who are pregnant or breastfeeding should consult their doctor before using AGALSIDASE BETA. The drug may have effects on the fetus or infant and should be used with caution during pregnancy or breastfeeding. Additionally, patients with certain heart conditions should avoid AGALSIDASE BETA. These heart conditions may worsen or cause adverse effects. In short, patients should read the instructions carefully and consult their doctor before using AGALSIDASE BETA to ensure their own safety.

Precautions

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  • Medication grading for pregnant women

    Requesting precautions for the drug AGALSIDASE BETA during the treatment of pregnancy:

    Women with a manufacturing enzyme deficiency during pregnancy, such as Gaucher's disease, may need to be treated with AGALSIDASE BETA. AGALSIDASE BETA should be used with caution during pregnancy and patients should consult their doctor to assess the risks.

    The risks of using AGALSIDASE BETA medication during pregnancy are unknown. Therefore, patients should inform their doctor immediately if they are pregnant or planning to become pregnant. The doctor will evaluate the potential risks and benefits of the drug to the fetus to help make the most appropriate decision.

    Medications should be used with caution during pregnancy, treatment should not be interrupted easily, and doses should not be adjusted on your own. Patients should use medications strictly in accordance with the doctor's recommendations and instructions, and receive regular monitoring and examinations to ensure the stability of the condition and the health of the fetus.

    The above are the preventive measures for using AGALSIDASE BETA during pregnancy. Patients should strictly follow the doctor's recommendations to ensure good treatment effects and the safety of the baby.

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