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drug database

project

Name/scientific name

5FLUCYTOSINE

Self-financed or subsidized by the Hospital Authority

Hospital Authority Drug Formulary

Indications

Candida infection, cryptococcal meningitis, fungal infection

body system

Antimicrobial

type 

antifungal drugs

category

Pagination

Drug introduction

5-Flucytosine is a drug used to treat fungal infections. It works by inhibiting nucleic acid synthesis within fungal cells. 5-Fluocytosine is commonly used to treat infections caused by fungi such as Candida, such as candidal meningitis. This drug is often combined with other antifungal drugs to increase its effectiveness.

In Hong Kong, doctors may consider 5-fluorocytosine as part of the treatment for fungal infections. Patients should pay close attention to possible side effects such as nausea, vomiting, diarrhea, etc. while taking this drug. During use of 5-fluorocytosine, blood indicators should be monitored regularly to ensure efficacy and safety.

Do not change your medication dosage or stop using 5-fluorocytosine on your own. Follow your doctor's advice and prescription instructions. If adverse reactions or questions arise, consult a medical professional immediately.

Dosage

Usage: Please use this drug under the guidance of a physician. It is usually recommended that adults take it orally in 2 to 4 divided doses per day, with each dose being 50 to 150 mg/kg. Children's dosage may vary based on weight and condition, please ask your physician for adjustment. It is recommended to take it on an empty stomach or with food as recommended by your doctor. Avoid taking it with high-calcium foods.

Dosage Guidelines: The initial dose is 50 mg/kg per day, which can be adjusted to 150 mg/kg per day according to the condition and physician's instructions. For adults, the maximum dose is usually no more than 8 grams daily. For children, adjust dosage according to physician recommendations. Dose adjustments should be based on the patient's renal function and severity of illness. Please use the medicine accurately according to your doctor's recommendations and do not adjust the dosage yourself.

side effect

5-Flucytosine is a drug used to treat fungal infections, but it can cause side effects when used. Common side effects include nausea, vomiting, diarrhea, and loss of appetite. A small number of patients may develop rash, headache, fatigue and abnormal liver function. Serious side effects include bone marrow suppression, liver toxicity, and allergic reactions. During use of 5-fluorocytosine, any abnormal symptoms should be closely monitored and prompt medical attention should be sought. If serious side effects occur, stop using the medication immediately and seek medical advice.

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Taboo

5-Flucytosine is an antifungal drug commonly used to treat fungal infections. However, the following contraindications should be noted when using 5-fluorocytosine:

1. **Allergic Reaction**: Patients allergic to 5-fluorocytosine are prohibited from using this drug. If allergic symptoms occur during use, the drug should be stopped immediately and seek medical advice.

2. **Severe Myelosuppression**: Patients with severe myelosuppression should avoid the use of 5-fluorocytosine, as this drug may further aggravate the impairment of bone marrow function.

3. **Severe liver dysfunction**: The use of 5-fluorocytosine should be contraindicated in patients with severe liver dysfunction because drug metabolism may cause further damage to the liver.

4. **Pregnant and lactating women**: Pregnant or lactating women should avoid using 5-fluorocytosine because the drug may cause adverse effects on the fetus or infant.

Before using 5-fluorocytosine, patients should inform their doctor in detail about their allergies, medical history, and other drugs they are taking to ensure the safe use of this drug. If you have any adverse reactions or questions, you should seek help from your doctor immediately.

Precautions

5-Fluocytosine is an antifungal drug used to treat fungal infections. When using it, you should strictly follow the doctor's instructions and do not increase or decrease the dosage on your own. Monitor regularly during use and pay close attention to possible side effects. If you have any discomfort or concerns, you should consult your doctor immediately.

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  • Medication grading for pregnant women

    Pregnant women should be cautious when taking 5-Flucytosine. According to research, the drug may harm a fetus, causing birth defects or other health problems. It is recommended that 5-fluorocytosine be used during pregnancy only under clear instructions from your doctor. If you are expecting to become pregnant, or are pregnant, you should inform your doctor immediately to determine whether there is a more appropriate treatment option.

    Remember to follow your doctor's advice and prescription instructions and do not change your dosage or stop taking your medication. If you find out that you are pregnant unexpectedly, you should tell your doctor immediately and discuss the possible risks and options.

    In short, when using 5-fluorocytosine or other drugs during pregnancy, you should carefully follow your doctor's advice to ensure the health of you and your fetus.

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